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Peroxiredoxin 5 Protects TGF-β Induced Fibrosis by Inhibiting Stat3 Activation in Rat Kidney Interstitial Fibroblast Cells

Renal fibrosis is a common final pathway of end-stage kidney disease which is induced by aberrant accumulation of myofibroblasts. This process is triggered by reactive oxygen species (ROS) and proinflammatory cytokines generated by various source of injured kidney cells. Peroxiredoxin 5 (Prdx5) is a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Choi, Hoon-In, Ma, Seong Kwon, Bae, Eun Hui, Lee, JongUn, Kim, Soo Wan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752225/
https://ncbi.nlm.nih.gov/pubmed/26872211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149266
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