Peroxiredoxin V (PrdxV) negatively regulates EGFR/Stat3-mediated fibrogenesis via a Cys48-dependent interaction between PrdxV and Stat3

Activation of the epidermal growth factor receptor (EGFR)/signal transducer and activator of transcription 3 (Stat3) signaling pathway has been reported to be associated with renal fibrosis. We have recently demonstrated that peroxiredoxin V (PrdxV) acted as an antifibrotic effector by inhibiting th...

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Publicat a:Sci Rep
Autors principals: Choi, Hoon-In, Kim, Dong-Hyun, Park, Jung Sun, Kim, In Jin, Kim, Chang Seong, Bae, Eun Hui, Ma, Seong Kwon, Lee, Tae-Hoon, Kim, Soo Wan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584630/
https://ncbi.nlm.nih.gov/pubmed/31217524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45347-0
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