Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

BACKGROUND: While localized prostate cancer (PCa) can be effectively cured, metastatic disease inevitably progresses to a lethal state called castration-resistant prostate cancer (CRPC). Emerging evidence suggests that aberrant epigenetic repression by the polycomb group (PcG) complexes fuels PCa pr...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Clermont, Pier-Luc, Crea, Francesco, Chiang, Yan Ting, Lin, Dong, Zhang, Amy, Wang, James Z. L., Parolia, Abhijit, Wu, Rebecca, Xue, Hui, Wang, Yuwei, Ding, Jiarui, Thu, Kelsie L., Lam, Wan L., Shah, Sohrab P., Collins, Colin C., Wang, Yuzhuo, Helgason, Cheryl D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751702/
https://ncbi.nlm.nih.gov/pubmed/26877821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0182-9
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