Organic Cation Transporter 1 (OCT1) mRNA expression in hepatocellular carcinoma as a biomarker for sorafenib treatment

BACKGROUND: The polyspecific organ cation transporter 1 (OCT1) is one of the most important active influx pumps for drugs like the kinase inhibitor sorafenib. The aim of this retrospective study was the definition of the role of intratumoral OCT1 mRNA expression in hepatocellular carcinoma (HCC) as...

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Bibliografiska uppgifter
I publikationen:BMC Cancer
Huvudupphovsmän: Grimm, Daniel, Lieb, Jonas, Weyer, Veronika, Vollmar, Johanna, Darstein, Felix, Lautem, Anja, Hoppe-Lotichius, Maria, Koch, Sandra, Schad, Arno, Schattenberg, Jörn M., Wörns, Marcus A., Weinmann, Arndt, Galle, Peter R., Zimmermann, Tim
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751638/
https://ncbi.nlm.nih.gov/pubmed/26872727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2150-3
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