Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization

Both type 1 and type 2 diabetes are associated with increased risk of cardiovascular disease. This is in part attributed to the effects of hyperglycemia on vascular endothelial and smooth muscle cells, but the underlying mechanisms are not fully understood. In diabetic animal models, hyperglycemia r...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Hien, Tran Thi, Turczyńska, Karolina M., Dahan, Diana, Ekman, Mari, Grossi, Mario, Sjögren, Johan, Nilsson, Johan, Braun, Thomas, Boettger, Thomas, Garcia-Vaz, Eliana, Stenkula, Karin, Swärd, Karl, Gomez, Maria F., Albinsson, Sebastian
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751395/
https://ncbi.nlm.nih.gov/pubmed/26683376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654384
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