Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization

Both type 1 and type 2 diabetes are associated with increased risk of cardiovascular disease. This is in part attributed to the effects of hyperglycemia on vascular endothelial and smooth muscle cells, but the underlying mechanisms are not fully understood. In diabetic animal models, hyperglycemia r...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Hien, Tran Thi, Turczyńska, Karolina M., Dahan, Diana, Ekman, Mari, Grossi, Mario, Sjögren, Johan, Nilsson, Johan, Braun, Thomas, Boettger, Thomas, Garcia-Vaz, Eliana, Stenkula, Karin, Swärd, Karl, Gomez, Maria F., Albinsson, Sebastian
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Molecular Bases of Disease
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751395/
https://ncbi.nlm.nih.gov/pubmed/26683376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654384
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