Generation and Characterisation of a Pax8-CreER(T2) Transgenic Line and a Slc22a6-CreER(T2) Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells

Genetically relevant mouse models need to recapitulate the hallmarks of human disease by permitting spatiotemporal gene targeting. This is especially important for replicating the biology of complex diseases like cancer, where genetic events occur in a sporadic fashion within developed somatic tissu...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Espana-Agusti, Judit, Zou, Xiangang, Wong, Kim, Fu, Beiyuan, Yang, Fengtang, Tuveson, David A., Adams, David J., Matakidou, Athena
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751286/
https://ncbi.nlm.nih.gov/pubmed/26866916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148055
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