Comparison of the Opn-CreER and Ck19-CreER Drivers in Bile Ducts of Normal and Injured Mouse Livers

Inducible cyclization recombinase (Cre) transgenic mouse strains are powerful tools for cell lineage tracing and tissue-specific knockout experiments. However, low efficiency or leaky expression can be important pitfalls. Here, we compared the efficiency and specificity of two commonly used cholangi...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lesaffer, Bram, Verboven, Elisabeth, Van Huffel, Leen, Moya, Iván M., van Grunsven, Leo A., Leclercq, Isabelle A., Lemaigre, Frédéric P., Halder, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Technical Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523626/
https://ncbi.nlm.nih.gov/pubmed/31027317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8040380
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