Genetic targeting of sprouting angiogenesis using Apln-CreER

Under pathophysiological conditions in adults, endothelial cells (ECs) sprout from pre-existing blood vessels to form new ones by a process termed angiogenesis. During embryonic development, Apelin (APLN) is robustly expressed in vascular ECs. In adult mice, however, APLN expression in the vasculatu...

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Udgivet i:Nat Commun
Main Authors: Liu, Qiaozhen, Hu, Tianyuan, He, Lingjuan, Huang, Xiuzhen, Tian, Xueying, Zhang, Hui, He, Liang, Pu, Wenjuan, Zhang, Libo, Sun, Heng, Fang, Jing, Yu, Ying, Duan, Shengzhong, Hu, Chaobo, Hui, Lijian, Zhang, Haibin, Quertermous, Thomas, Xu, Qingbo, Red-Horse, Kristy, Wythe, Joshua D., Zhou, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309445/
https://ncbi.nlm.nih.gov/pubmed/25597280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7020
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