Cytosolic Phospholipase A(2)α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension

BACKGROUND: The kidney plays an important role in regulating blood pressure (BP). cPLA2α in the kidney is activated by various agents including angiotensin II (Ang II) and selectively releases arachidonic acid (AA) from tissue lipids, generating pro- and antihypertensive eicosanoids. Since activatio...

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Detalles Bibliográficos
Publicado en:Am J Hypertens
Main Authors: Khan, Nayaab S., Song, Chi Young, Thirunavukkarasu, Shyamala, Fang, Xiao R., Bonventre, Joseph V., Malik, Kafait U.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751243/
https://ncbi.nlm.nih.gov/pubmed/26045535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpv083
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