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Autophagy-Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin Analog
We have synthesized a novel derivative of Digitoxin, termed “MonoD”, which demonstrates cytotoxic effects in lung cancer cells with much higher potency as compared to Digitoxin. Our data show that within 1 h of MonoD treatment, H460 cells showed increased oxidative stress, increased formation of aut...
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| Publicado en: | J Cell Physiol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4751068/ https://ncbi.nlm.nih.gov/pubmed/26264876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25129 |
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