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Induction of WT1-specific human CD8(+) T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice
Induction of specific immune response against therapy-resistant tumor cells can potentially improve clinical outcomes in malignancies. To optimize immunotherapy in the clinic, we aimed to create an in vivo model enabling us to analyze human cytotoxic T-lymphocyte (CTL) responses against human malign...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4751022/ https://ncbi.nlm.nih.gov/pubmed/26702062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-604777 |
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