Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells

Human acute myeloid leukemia (AML) originates from rare leukemia stem cells (LSCs). Because these chemotherapy-resistant LSCs are thought to underlie disease relapse, effective therapeutic strategies specifically targeting these cells may be beneficial. Here, we report identification of a primary hu...

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Bibliographic Details
Main Authors: Saito, Yoriko, Kitamura, Hiroshi, Hijikata, Atsushi, Tomizawa-Murasawa, Mariko, Tanaka, Satoshi, Takagi, Shinsuke, Uchida, Naoyuki, Suzuki, Nahoko, Sone, Akiko, Najima, Yuho, Ozawa, Hidetoshi, Wake, Atsushi, Taniguchi, Shuichi, Shultz, Leonard D., Ohara, Osamu, Ishikawa, Fumihiko
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005290/
https://ncbi.nlm.nih.gov/pubmed/20371479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000349
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