Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR

We studied Mesenchymal Stromal Cells (MSC) effects in experimental Unilateral Ureteral Obstruction (UUO), a fibrogenic renal disease. Rats were divided in 5 groups: sham, UUO, MSC treated-UUO, ACEi treated-UUO, MSC+ACEi treated- UUO. Data were collected at 1, 7, 21 days. UUO induced monocyte renal i...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Gregorini, Marilena, Corradetti, Valeria, Rocca, Chiara, Pattonieri, Eleonora Francesca, Valsania, Teresa, Milanesi, Samantha, Serpieri, Nicoletta, Bedino, Giulia, Esposito, Pasquale, Libetta, Carmelo, Avanzini, Maria Antonietta, Mantelli, Melissa, Ingo, Daniela, Peressini, Sabrina, Albertini, Riccardo, Dal Canton, Antonio, Rampino, Teresa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750962/
https://ncbi.nlm.nih.gov/pubmed/26866372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148542
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