Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR

We studied Mesenchymal Stromal Cells (MSC) effects in experimental Unilateral Ureteral Obstruction (UUO), a fibrogenic renal disease. Rats were divided in 5 groups: sham, UUO, MSC treated-UUO, ACEi treated-UUO, MSC+ACEi treated- UUO. Data were collected at 1, 7, 21 days. UUO induced monocyte renal i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gregorini, Marilena, Corradetti, Valeria, Rocca, Chiara, Pattonieri, Eleonora Francesca, Valsania, Teresa, Milanesi, Samantha, Serpieri, Nicoletta, Bedino, Giulia, Esposito, Pasquale, Libetta, Carmelo, Avanzini, Maria Antonietta, Mantelli, Melissa, Ingo, Daniela, Peressini, Sabrina, Albertini, Riccardo, Dal Canton, Antonio, Rampino, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750962/
https://ncbi.nlm.nih.gov/pubmed/26866372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148542
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