Synergistic Malaria Parasite Killing by Two Types of Plasmodial Surface Anion Channel Inhibitors

Malaria parasites increase their host erythrocyte’s permeability to a broad range of ions and organic solutes. The plasmodial surface anion channel (PSAC) mediates this uptake and is an established drug target. Development of therapies targeting this channel is limited by several problems including...

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Pubblicato in:PLoS One
Autori principali: Pain, Margaret, Fuller, Alexandra W., Basore, Katherine, Pillai, Ajay D., Solomon, Tsione, Bokhari, Abdullah A. B., Desai, Sanjay A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750852/
https://ncbi.nlm.nih.gov/pubmed/26866812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149214
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