A Cell-Based High-Throughput Screen Validates the Plasmodial Surface Anion Channel As an Antimalarial Target

The plasmodial surface anion channel (PSAC) is an unusual small-conductance ion channel induced on erythrocytes infected with plasmodia, including parasites responsible for human malaria. Although broadly available inhibitors produce microscopic clearance of parasite cultures at high concentrations...

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Библиографические подробности
Главные авторы: Pillai, Ajay D., Pain, Margaret, Solomon, Tsione, Bokhari, Abdullah A. B., Desai, Sanjay A.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872968/
https://ncbi.nlm.nih.gov/pubmed/20101003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.062711
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