Synergistic Malaria Parasite Killing by Two Types of Plasmodial Surface Anion Channel Inhibitors

Malaria parasites increase their host erythrocyte’s permeability to a broad range of ions and organic solutes. The plasmodial surface anion channel (PSAC) mediates this uptake and is an established drug target. Development of therapies targeting this channel is limited by several problems including...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pain, Margaret, Fuller, Alexandra W., Basore, Katherine, Pillai, Ajay D., Solomon, Tsione, Bokhari, Abdullah A. B., Desai, Sanjay A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750852/
https://ncbi.nlm.nih.gov/pubmed/26866812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149214
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