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Characterization of Polymyxin B Biodistribution and Disposition in an Animal Model

Despite dose-limiting nephrotoxicity concerns, polymyxin B has resurged as the treatment of last resort for multidrug-resistant Gram-negative bacterial infections. However, the pharmacokinetic, pharmacodynamic, and nephrotoxic properties of polymyxin B still are not thoroughly understood. The object...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Manchandani, Pooja, Zhou, Jian, Ledesma, Kimberly R., Truong, Luan D., Chow, Diana S.-L., Eriksen, Jason L., Tam, Vincent H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750689/
https://ncbi.nlm.nih.gov/pubmed/26643340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02445-15
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