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Inhibition of Pseudomonas aeruginosa ExsA DNA-Binding Activity by N-Hydroxybenzimidazoles

The Pseudomonas aeruginosa type III secretion system (T3SS) is a primary virulence determinant and a potential target for antivirulence drugs. One candidate target is ExsA, a member of the AraC family of DNA-binding proteins required for expression of the T3SS. A previous study identified small mole...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Marsden, Anne E., King, Jessica M., Spies, M. Ashley, Kim, Oak K., Yahr, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750669/
https://ncbi.nlm.nih.gov/pubmed/26574012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02242-15
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