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Self-trimerization of ExsD limits inhibition of the Pseudomonas aeruginosa transcriptional activator ExsA in vitro

The opportunistic pathogen Pseudomonas aeruginosa ranks among leading causes of nosocomial infections. The type III secretion system (T3SS) aids acute P. aeruginosa infections by injecting potent cytotoxins into host cells to suppress the host's innate immune response. Expression of all T3SS-re...

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Detalhes bibliográficos
Main Authors: Bernhards, Robert C., Marsden, Anne E., Esher, Shannon K., Yahr, Timothy L., Schubot, Florian D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621117/
https://ncbi.nlm.nih.gov/pubmed/23279839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12103
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