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ExsD Inhibits Expression of the Pseudomonas aeruginosa Type III Secretion System by Disrupting ExsA Self-Association and DNA Binding Activity

Pseudomonas aeruginosa utilizes a type III secretion system (T3SS) to damage eukaryotic host cells and evade phagocytosis. Transcription of the T3SS regulon is controlled by ExsA, a member of the AraC/XylS family of transcriptional regulators. ExsA-dependent transcription is coupled to type III secr...

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Detalhes bibliográficos
Main Authors: Brutinel, Evan D., Vakulskas, Christopher A., Yahr, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832532/
https://ncbi.nlm.nih.gov/pubmed/20008065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01457-09
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