Towards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling

Because of the recent awareness that vancomycin doses should aim to meet a target area under the concentration-time curve (AUC) instead of trough concentrations, more aggressive dosing regimens are warranted also in the pediatric population. In this study, both neonatal and pediatric pharmacokinetic...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Janssen, Esther J. H., Välitalo, Pyry A. J., Allegaert, Karel, de Cock, Roosmarijn F. W., Simons, Sinno H. P., Sherwin, Catherine M. T., Mouton, Johan W., van den Anker, Johannes N., Knibbe, Catherijne A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750654/
https://ncbi.nlm.nih.gov/pubmed/26643337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01968-15
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