Retinol as a cofactor for PKCδ-mediated impairment of insulin sensitivity in a mouse model of diet-induced obesity

We previously defined that the mitochondria-localized PKCδ signaling complex stimulates the conversion of pyruvate to acetyl-coenzyme A by the pyruvate dehydrogenase complex. We demonstrated in vitro and ex vivo that retinol supplementation enhances ATP synthesis in the presence of the PKCδ signalos...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Shabrova, Elena, Hoyos, Beatrice, Vinogradov, Valerie, Kim, Youn-Kyung, Wassef, Lesley, Leitges, Michael, Quadro, Loredana, Hammerling, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2016
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750423/
https://ncbi.nlm.nih.gov/pubmed/26671999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-281543
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