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Two protein kinase C isoforms, δ and ε, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex

Energy production in mitochondria is a multistep process that requires coordination of several subsystems. While reversible phosphorylation is emerging as the principal tool, it is still unclear how this signal network senses the workloads of processes as different as fuel procurement, catabolism in...

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Detalhes bibliográficos
Main Authors: Gong, Jianli, Hoyos, Beatrice, Acin-Perez, Rebeca, Vinogradov, Valerie, Shabrova, Elena, Zhao, Feng, Leitges, Michael, Fischman, Donald, Manfredi, Giovanni, Hammerling, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405274/
https://ncbi.nlm.nih.gov/pubmed/22573912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-197376
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