Occludin controls HIV transcription in brain pericytes via regulation of SIRT-1 activation

HIV invades the brain early after infection; however, its interactions with the cells of the blood–brain barrier (BBB) remain poorly understood. Our goal was to evaluate the role of occludin, one of the tight junction proteins that regulate BBB functions in HIV infection of BBB pericytes. We provide...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Castro, Victor, Bertrand, Luc, Luethen, Mareen, Dabrowski, Sebastian, Lombardi, Jorge, Morgan, Laura, Sharova, Natalia, Stevenson, Mario, Blasig, Ingolf E., Toborek, Michal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2016
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750406/
https://ncbi.nlm.nih.gov/pubmed/26601824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-277673
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