Occludin controls HIV transcription in brain pericytes via regulation of SIRT-1 activation

HIV invades the brain early after infection; however, its interactions with the cells of the blood–brain barrier (BBB) remain poorly understood. Our goal was to evaluate the role of occludin, one of the tight junction proteins that regulate BBB functions in HIV infection of BBB pericytes. We provide...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Castro, Victor, Bertrand, Luc, Luethen, Mareen, Dabrowski, Sebastian, Lombardi, Jorge, Morgan, Laura, Sharova, Natalia, Stevenson, Mario, Blasig, Ingolf E., Toborek, Michal
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2016
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750406/
https://ncbi.nlm.nih.gov/pubmed/26601824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-277673
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