Occludin, caveolin‐1, and Alix form a multi‐protein complex and regulate HIV‐1 infection of brain pericytes

HIV‐1 enters the brain by altering properties of the blood‐brain barrier (BBB). Recent evidence indicates that among cells of the BBB, pericytes are prone to HIV‐1 infection. Occludin (ocln) and caveolin‐1 (cav‐1) are critical determinants of BBB integrity that can regulate barrier properties of the...

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Bibliographic Details
Published in:FASEB J
Main Authors: Torices, Silvia, Roberts, Samantha A., Park, Minseon, Malhotra, Arun, Toborek, Michal
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686148/
https://ncbi.nlm.nih.gov/pubmed/33058236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001562R
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