Parallelism of DOG1 expression with recurrence risk in gastrointestinal stromal tumors bearing KIT or PDGFRA mutations

BACKGROUND: Gastrointestinal stromal tumors (GISTs) are characterized by mutations of KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) or PDGFRA (platelet-derived growth factor receptor α) that may be efficiently targeted by tyrosine kinase inhibitors (TKI). Notwithstanding the ea...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Rizzo, Francesca Maria, Palmirotta, Raffaele, Marzullo, Andrea, Resta, Nicoletta, Cives, Mauro, Tucci, Marco, Silvestris, Franco
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750215/
https://ncbi.nlm.nih.gov/pubmed/26867653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2111-x
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