Skeletal troponin C reduces contractile sensitivity to acidosis in cardiac myocytes from transgenic mice.

Depressed contractile function plays a primary role in the pathophysiology of acute myocardial ischemia. Intracellular acidification is an important factor underlying the inhibition of force production in the ischemic myocardium. The effect of acidosis to depress contractility is markedly greater in...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Metzger, J M, Parmacek, M S, Barr, E, Pasyk, K, Lin, W I, Cochrane, K L, Field, L J, Leiden, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47496/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.9036
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