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Muscle niche-driven Insulin-Notch-Myc cascade reactivates dormant Adult Muscle Precursors in Drosophila

How stem cells specified during development keep their non-differentiated quiescent state, and how they are reactivated, remain poorly understood. Here, we applied a Drosophila model to follow in vivo behavior of adult muscle precursors (AMPs), the transient fruit fly muscle stem cells. We report th...

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Pubblicato in:eLife
Autori principali: Aradhya, Rajaguru, Zmojdzian, Monika, Da Ponte, Jean Philippe, Jagla, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749548/
https://ncbi.nlm.nih.gov/pubmed/26650355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08497
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