Dissecting Pathogenetic Mechanisms and Therapeutic Strategies in <i>Drosophila</i> Models of Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1), the most common cause of adult-onset muscular dystrophy, is autosomal dominant, multisystemic disease with characteristic symptoms including myotonia, heart defects, cataracts and testicular atrophy. DM1 disease is being successfully modelled in <i>Drosophila&l...

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Main Authors: Anissa Souidi, Monika Zmojdzian, Krzysztof Jagla
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Assuntos:
DM1
muscular dystrophy
animal model
<i>Drosophila</i>
drug screen
genetic screen
therapeutic targets
Acceso en liña:https://www.mdpi.com/1422-0067/19/12/4104
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