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Scintillation proximity assay (SPA) as a new approach to determine a ligand’s kinetic profile. A case in point for the adenosine A(1) receptor

Scintillation proximity assay (SPA) is a radio-isotopic technology format used to measure a wide range of biological interactions, including drug-target binding affinity studies. The assay is homogeneous in nature, as it relies on a “mix and measure” format. It does not involve a filtration step to...

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Foilsithe in:Purinergic Signal
Main Authors: Xia, Lizi, de Vries, Henk, IJzerman, Ad P., Heitman, Laura H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Netherlands 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749533/
https://ncbi.nlm.nih.gov/pubmed/26647040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-015-9485-0
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