Overexpression of Cystathionine γ-Lyase Suppresses Detrimental Effects of Spinocerebellar Ataxia Type 3

Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) disorder caused by a CAG repeat expansion in the ataxin-3 (ATXN3) gene resulting in toxic protein aggregation. Inflammation and oxidative stress are considered secondary factors contributing to the progression of this neurodegenerative...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Mol Med
Main Authors: Snijder, Pauline M, Baratashvili, Madina, Grzeschik, Nicola A, Leuvenink, Henri G D, Kuijpers, Lucas, Huitema, Sippie, Schaap, Onno, Giepmans, Ben N G, Kuipers, Jeroen, Miljkovic, Jan Lj, Mitrovic, Aleksandra, Bos, Eelke M, Szabó, Csaba, Kampinga, Harm H, Dijkers, Pascale F, den Dunnen, Wilfred F A, Filipovic, Milos R, van Goor, Harry, Sibon, Ody C M
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Feinstein Institute Press 2015
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749487/
https://ncbi.nlm.nih.gov/pubmed/26467707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00221
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla