PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer

Cachexia is a wasting syndrome associated with elevated basal energy expenditure and loss of adipose and muscle tissues. It accompanies many chronic diseases including renal failure and cancer and is an important risk factor for mortality. Our recent work demonstrated that tumor-derived PTHrP drives...

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Publicat a:Cell Metab
Autors principals: Kir, Serkan, Komaba, Hirotaka, Garcia, Ana P., Konstantinos, P. Economopoulos, Wei, Liu, Beate, Lanske, Richard, A. Hodin, Bruce, M. Spiegelman
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749423/
https://ncbi.nlm.nih.gov/pubmed/26669699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.11.003
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