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Tumor-derived PTHrP Triggers Adipose Tissue Browning and Cancer Cachexia
SUMMARY: Cachexia is a wasting disorder of adipose and skeletal muscle tissues that leads to profound weight loss and frailty. About half of all cancer patients suffer from cachexia, which impairs quality of life, limits cancer therapy and decreases survival. One key characteristic of cachexia is el...
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Publicado no: | Nature |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224962/ https://ncbi.nlm.nih.gov/pubmed/25043053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13528 |
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