Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy

Mutations of the Adenomatous polyposis coli (APC) gene are common and strongly associated with the development of colorectal adenomas and carcinomas. While extensively studied in modern populations, reports on visceral tumors in ancient populations are scarce. To the best of our knowledge, genetic c...

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Foilsithe in:PLoS One
Main Authors: Feldman, Michal, Hershkovitz, Israel, Sklan, Ella H., Kahila Bar-Gal, Gila, Pap, Ildikó, Szikossy, Ildikó, Rosin-Arbesfeld, Rina
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749341/
https://ncbi.nlm.nih.gov/pubmed/26863316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147217
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