Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy

Mutations of the Adenomatous polyposis coli (APC) gene are common and strongly associated with the development of colorectal adenomas and carcinomas. While extensively studied in modern populations, reports on visceral tumors in ancient populations are scarce. To the best of our knowledge, genetic c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Feldman, Michal, Hershkovitz, Israel, Sklan, Ella H., Kahila Bar-Gal, Gila, Pap, Ildikó, Szikossy, Ildikó, Rosin-Arbesfeld, Rina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749341/
https://ncbi.nlm.nih.gov/pubmed/26863316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147217
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