Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy

Mutations of the Adenomatous polyposis coli (APC) gene are common and strongly associated with the development of colorectal adenomas and carcinomas. While extensively studied in modern populations, reports on visceral tumors in ancient populations are scarce. To the best of our knowledge, genetic c...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Feldman, Michal, Hershkovitz, Israel, Sklan, Ella H., Kahila Bar-Gal, Gila, Pap, Ildikó, Szikossy, Ildikó, Rosin-Arbesfeld, Rina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749341/
https://ncbi.nlm.nih.gov/pubmed/26863316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147217
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