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Recognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched cis-syn Thymine Dimer Lesion
[Image: see text] Mammalian global genomic nucleotide excision repair requires lesion recognition by XPC, whose detailed binding mechanism remains to be elucidated. Here we have delineated the dynamic molecular pathway and energetics of lesion-specific and productive binding by the Rad4/yeast XPC le...
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| Опубликовано в: : | Biochemistry |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American
Chemical Society
2015
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748833/ https://ncbi.nlm.nih.gov/pubmed/26270861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00840 |
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