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LPS- or Pseudomonas aeruginosa-mediated activation of the macrophage TLR4 signaling cascade depends on membrane lipid composition

It is well known that PUFA impede the LPS-mediated activation of the transcription factor NFkappaB. However, the underlying mode of action has not been clarified yet. To address this issue in a comprehensive approach, we used the monocyte/macrophage cell line RAW264.7 to investigate the consequences...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Schoeniger, Axel, Fuhrmann, Herbert, Schumann, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748739/
https://ncbi.nlm.nih.gov/pubmed/26870615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1663
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