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Lipid raft localization of TLR2 and its co-receptors is independent of membrane lipid composition

BACKGROUND: Toll like receptors (TLRs) are an important and evolutionary conserved class of pattern recognition receptors associated with innate immunity. The recognition of Gram-positive cell wall constituents strongly depends on TLR2. In order to be functional, TLR2 predominantly forms a heterodim...

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Библиографические подробности
Опубликовано в: :PeerJ
Главные авторы: Hellwing, Christine, Schoeniger, Axel, Roessler, Claudia, Leimert, Anja, Schumann, Julia
Формат: Artigo
Язык:Inglês
Опубликовано: PeerJ Inc. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757419/
https://ncbi.nlm.nih.gov/pubmed/29312832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4212
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