Modulating RNA Alignment Using Directional Dynamic Kinks: Application in Determining an Atomic-Resolution Ensemble for a Hairpin using NMR Residual Dipolar Couplings

Approaches that combine experimental data and computational molecular (MD) dynamics to determine atomic resolution ensembles of biomolecules require the measurement of abundant experimental data. NMR residual dipolar couplings (RDCs) carry rich dynamics information, however, difficulties in modulati...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Salmon, Loïc, Giambaşu, George M., Nikolova, Evgenia N., Petzold, Katja, Bhattacharya, Akash, Case, David A., Al-Hashimi, Hashim M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748170/
https://ncbi.nlm.nih.gov/pubmed/26306428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07229
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