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Structural fidelity and NMR relaxation analysis in a prototype RNA hairpin

RNA hairpins are widespread and very stable motifs that contribute decisively to RNA folding and biological function. The GTP1G2C3A4C5U6U7C8G9G10U11G12C13C14 construct (with a central UUCG tetraloop) has been extensively studied by solution NMR, and offers and excellent opportunity to evaluate the s...

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Détails bibliographiques
Publié dans:RNA
Auteurs principaux: Giambaşu, George M., York, Darrin M., Case, David A.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408802/
https://ncbi.nlm.nih.gov/pubmed/25805858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047357.114
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