Folate Receptor Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is a recalcitrant malignancy with no available targeted therapy. Off target effects and poor bioavailability of the FDA approved anti-obesity drug orlistat hinder its clinical translation as a repurposed new drug against TNBC. Here we demonstrate a newly engineer...

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Опубликовано в: :Mol Cancer Ther
Главные авторы: Paulmurugan, Ramasamy, Bhethanabotla, Rohith, Mishra, Kaushik, Devulapally, Rammohan, Foygel, Kira, Sekar, Thillai V, Ananta, Jeyarama S, Massoud, Tarik F, Joy, Abraham
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747857/
https://ncbi.nlm.nih.gov/pubmed/26553061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0579
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