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Intrinsic functional defects of ILC2 impair innate allergic inflammation in PLZF-deficient mice

BACKGROUND: The transcription factor PLZF is transiently expressed during the development of ILC2s but is not present at the mature stage. We hypothesized that PLZF-deficient ILC2s have functional defects in the innate allergic response and represent a tool for studying innate immunity in a mouse wi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Allergy Clin Immunol
Päätekijät: Verhoef, Philip A., Constantinides, Michael G., McDonald, Benjamin D., Urban, Joseph F., Sperling, Anne I., Bendelac, Albert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747811/
https://ncbi.nlm.nih.gov/pubmed/26602165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.07.050
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