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Intrinsic functional defects of ILC2 impair innate allergic inflammation in PLZF-deficient mice
BACKGROUND: The transcription factor PLZF is transiently expressed during the development of ILC2s but is not present at the mature stage. We hypothesized that PLZF-deficient ILC2s have functional defects in the innate allergic response and represent a tool for studying innate immunity in a mouse wi...
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| Publicado no: | J Allergy Clin Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747811/ https://ncbi.nlm.nih.gov/pubmed/26602165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.07.050 |
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