Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers

Uterine leiomyomas are common benign smooth muscle tumors that impose a major burden on women’s health. Recent sequencing studies have revealed recurrent and mutually exclusive mutations in leiomyomas, suggesting the involvement of molecularly distinct pathways. In this study, we explored transcript...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Mehine, Miika, Kaasinen, Eevi, Heinonen, Hanna-Riikka, Mäkinen, Netta, Kämpjärvi, Kati, Sarvilinna, Nanna, Aavikko, Mervi, Vähärautio, Anna, Pasanen, Annukka, Bützow, Ralf, Heikinheimo, Oskari, Sjöberg, Jari, Pitkänen, Esa, Vahteristo, Pia, Aaltonen, Lauri A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747776/
https://ncbi.nlm.nih.gov/pubmed/26787895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518752113
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