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The LMO2 oncogene regulates DNA replication in hematopoietic cells

Oncogenic transcription factors are commonly activated in acute leukemias and subvert normal gene expression networks to reprogram hematopoietic progenitors into preleukemic stem cells, as exemplified by LIM-only 2 (LMO2) in T-cell acute lymphoblastic leukemia (T-ALL). Whether or not these oncoprote...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sincennes, Marie-Claude, Humbert, Magali, Grondin, Benoît, Lisi, Véronique, Veiga, Diogo F. T., Haman, André, Cazaux, Christophe, Mashtalir, Nazar, Affar, EL Bachir, Verreault, Alain, Hoang, Trang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747768/
https://ncbi.nlm.nih.gov/pubmed/26764384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515071113
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