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Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade
Cocaine exerts its behavioral stimulant effects by facilitating synaptic actions of neurotransmitters such as dopamine and serotonin. It is also neurotoxic and broadly cytotoxic, leading to overdose deaths. We demonstrate that the cytotoxic actions of cocaine reflect selective enhancement of autopha...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747760/ https://ncbi.nlm.nih.gov/pubmed/26787898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524860113 |
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