Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila

Lifespan of laboratory animals can be increased by genetic, pharmacological, and dietary interventions. Increased expression of genes involved in xenobiotic metabolism, together with resistance to xenobiotics, are frequent correlates of lifespan extension in the nematode worm Caenorhabditis elegans,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Afschar, Sonita, Toivonen, Janne M., Hoffmann, Julia Marianne, Tain, Luke Stephen, Wieser, Daniela, Finlayson, Andrew John, Driege, Yasmine, Alic, Nazif, Emran, Sahar, Stinn, Julia, Froehlich, Jenny, Piper, Matthew D., Partridge, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747718/
https://ncbi.nlm.nih.gov/pubmed/26787908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515137113
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